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9 news posts in Frontiers in Science

Earth science

14 Nov 2023

New study highlights need to address risk of continued global warming after net zero

by Liad Hollender, Frontiers science writer Image: Shutterstock.com The UN Climate Panel’s latest best estimate is that global warming will end once we reach net zero CO2 emissions – but a study in Frontiers in Science warns significant warming could still occur. Researchers including those from Imperial College London and University of Exeter assess factors controlling global temperatures post ‘net zero’ and offer a pioneering framework for better estimating climate change risks. These risks must inform climate mitigation and adaptation policies to protect future generations.  From scorching heatwaves to torrential downpours and devastating storms, the disastrous effects of global warming are sweeping across the world. Being the predicted outcome of burning fossil fuels, our best and only plan to limit warming is to reduce CO2 emissions from human activities to ‘net zero’ – where the amount of CO2 we emit into the atmosphere is equal to the amount we remove from it. To keep within the 1.5°C limit of the 2015 Paris Agreement, this needs to happen as soon as possible.   Though the scientific community’s current best estimate from models is that global warming will stop at net zero, an article published in Frontiers in Science raises a red flag.  […]

Image: Prof Gerold Stucki

Health

31 May 2023

‘Rethinking health beyond disability and disease’

by Liad Hollender, Frontiers science writer Image: Prof Gerold Stucki Is there more to health than just the absence of disease? According to a team of researchers from Swiss Paraplegic Research and the University of Lucerne, the answer is a resounding ‘yes’. In an article published in Frontiers in Science, the researchers explain how ‘human functioning’ – a new assessment of health – could revolutionize healthcare, and even help advance the UN 2030 Sustainable Development Agenda. But what is human functioning and why is it such a powerful concept? To find out, Frontiers spoke with the team – Prof Jerome Bickenbach, Prof Sara Rubinelli, Cristiana Baffone, and Prof Gerold Stucki. How would you define human functioning? Gerold: Functioning is a concept developed by the World Health Organization (WHO), which constitutes a rethinking of health that goes beyond disability and disease. It encompasses people’s biological health as well as their ‘lived health’ – the activities they perform in their daily lives. What activities? Everything from eating and grooming, to working and socializing. This way of thinking is important because while it’s true that our biological health affects what we can do, features of our environment can either improve this capacity or […]

Featured news

31 May 2023

New health indicator can revolutionize how we measure and achieve well-being

by Liad Hollender, Frontiers science writer Image: Shutterstock Researchers reveal how a new assessment of health called ‘human functioning’ could bridge health and well-being, with far reaching benefits to individuals and society as a whole. Publishing in Frontiers in Science, the authors chart a plan for implementing human functioning into health systems, by recognizing it as a major health indicator alongside mortality and morbidity and establishing a new scientific field called human functioning sciences. The term ‘well-being’ entered popular vocabulary during the Covid-19 pandemic soon after ‘lockdown’ and ‘quarantine’. We quickly discovered that without the ability to take walks, socialize, and work, our well-being suffered. Health was suddenly more than just the state of our bodies – it also depended on our ability to engage in activities that matter to us. Though this was a revelation to many, the World Health Organization (WHO) had already begun this rethinking of health. It created a new concept and assessment framework to capture the multi-dimensional nature of our everyday health experience, called ‘human functioning. “Despite its great promise, this new tool has not been implemented widely in healthcare and policy. Our team’s goal is to make it happen,” said Prof Gerold Stucki, a […]

Featured news

28 Feb 2023

From anti-antibiotics to extinction therapy: how evolutionary thinking can transform medicine

by Liad Hollender, Frontiers science writer Image: Shutterstock Antibiotic resistance, cancer, and obesity are on the rise despite intense drug development efforts. To curb this trend, scientists release a research plan for evolutionary medicine, guiding the way for innovative biomedical therapies and more effective public health measures.  The word ‘evolution’ may bring to mind dusty dinosaur bones, but it impacts our health every day. For example, even though antibiotics were invented only a century ago, the evolution of antibiotic resistance is already a major concern. The rise in modern health problems such as obesity can also be traced back to evolutionary principles.    An article published in Frontiers in Science demonstrates how applying an evolutionary perspective to medicine can inspire new ways of preventing and treating disease.   “Evolutionary medicine holds promise to transform our understanding of why we get sick and strengthen our ability to protect human health,” said Dr Barbara Natterson-Horowitz of Harvard University and the University of California, Los Angeles. “We came together with experts across many fields to create an overarching research agenda for this field.”    “Our aim is to drive new biomedical innovations and effective public health measures, for everything from infectious disease and pandemics to cancer, […]

Health

28 Feb 2023

‘We cannot change the human body, but we can change the environment’

by Liad Hollender, Frontiers science writer Dr Barbara Natterson-Horowitz (a cardiologist) and Prof Daniel Blumstein (a behavioral ecologist) were faculty members at the Los Angeles campus of the University of California for decades before they met. Since their serendipitous encounter in the mid-2000s at a lecture on evolution, the two have become prolific scientific collaborators. They are leading researchers in the emerging field of evolutionary medicine, which applies insights from ecology and evolution to drive biomedical innovation and public health reform.  Their most recent article, published in Frontiers in Science, brings together diverse experts to chart a research agenda of staggering scope. Their aim is to tackle major health challenges by applying an evolutionary perspective to everything from antibiotic resistance and drug-resistant cancers to obesity, diabetes, and other ‘modern’ diseases. We met with them to learn more about this disruptive field.    Evolution and medicine seem like very distinct disciplines. How are they related?    Barbara: There is a famous saying – ‘Nothing in biology makes sense except in the light of evolution’ by Theodosius Dobzhansky. But what is medicine if not the biology of the human body and mind? Viewing health through the lens of evolutionary biology helps explain why we […]

Featured news

28 Feb 2023

Scientists unveil plan to create biocomputers powered by human brain cells

by Liad Hollender, Frontiers science writer Credit: Thomas Hartung, Johns Hopkins University Despite AI’s impressive track record, its computational power pales in comparison with that of the human brain. Scientists today unveil a revolutionary path to drive computing forward: organoid intelligence (OI), where lab-grown brain organoids serve as biological hardware. “This new field of biocomputing promises unprecedented advances in computing speed, processing power, data efficiency, and storage capabilities – all with lower energy needs,” say the authors in an article published in Frontiers in Science.  Artificial intelligence (AI) has long been inspired by the human brain. This approach proved highly successful: AI boasts impressive achievements – from diagnosing medical conditions to composing poetry. Still, the original model continues to outperform machines in many ways. This is why, for example, we can ‘prove our humanity’ with trivial image tests online. What if instead of trying to make AI more brain-like, we went straight to the source?  Scientists across multiple disciplines are working to create revolutionary biocomputers where three-dimensional cultures of brain cells, called brain organoids, serve as biological hardware. They describe their roadmap for realizing this vision in the journal Frontiers in Science.   “We call this new interdisciplinary field ‘organoid intelligence’ […]

Robotics and AI

28 Feb 2023

‘My dream is for AI and brain organoids to explore each other’s capabilities’

by Liad Hollender, Frontiers science writer Image: Prof Thomas Hartung Over just a few decades, computers shrunk from massive installations to slick devices that fit in our pockets. But this dizzying trend might end soon, because we simply can’t produce small enough components. To keep driving computing forward, scientists are looking for alternative approaches. An article published in Frontiers in Science presents a revolutionary strategy, called organoid intelligence.   This emerging scientific field aims to create biocomputers where lab-grown brain organoids (three-dimensional brain-cell cultures) serve as biological hardware. According to the authors, this technology could also drive progress in biomedicine, providing unprecedented insight into the human brain.  To learn more about this exciting new field, we interviewed the senior author of the article, Prof Thomas Hartung. He is the director of the Center for Alternatives to Animal Testing in Europe (CAAT-Europe), and a professor at Johns Hopkins University’s Bloomberg School of Public Health.  How do you define organoid intelligence? Reproducing cognitive functions – such as learning and sensory processing – in a lab-grown human-brain model.   How did this idea emerge? I’m a pharmacologist and toxicologist, so I’m interested in developing medicines and identifying substances that are dangerous to our health, specifically […]